Cisterna Biologics
High quality mRNA for therapeutic application
Founders
Not read from YC yet; the weekly run fills these in.
Same space
Competitors
Closest in what they build, same category.
Adjacent
Overlapping tags, a different niche.
SynsoryBioW24"If-then" conditional logic for protein drugsShared: synthetic biology, biotech, therapeuticsActive
Granza BioW24Building programmable therapeutics for the immune systemShared: synthetic biology, biotech, therapeuticsActive
Engage BioW22Potent, durable, and redosable non-viral genetic medicinesShared: synthetic biology, biotech, therapeuticsAcquired
Kopra BioS24Genetically engineered viruses that teach your immune system to kill…Shared: synthetic biology, biotech, therapeuticsActive
Gerostate AlphaS18Developing novel therapeutics for aging and chronic diseaseShared: biotech, therapeuticsInactive
Also from S22
Batchmates in Summer 2022.
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LaminS22Open data platform for traceable, multimodal AIActive
QuinnS22Your biopharma team, from molecule design to portfolio strategyActive
100xS22Create, Share, and Monetize AI AgentsActive
About Cisterna Biologics
Founded in 2022 and based in San Diego, California, Cisterna Biologics is a technology company. It aims to solve some of the challenges currently facing the biotech industry to develop mRNA-based therapeutics – quality, quantity, longevity and cost of mRNA. As mRNA technology matures, it becomes imperative that these issues are solved so we can fully explore mRNA's endless possibilities as a therapeutic. Cisterna uses proprietary technologies to either remove a contaminant at its source or replace the source itself. For example, to remove double-stranded RNA (dsRNA), we use ribozymes - molecular scissors - to precisely cut the mRNA at its 3’ end. This assures not only 3’ homogeneity, but also eliminates dsRNA, which are primarily produced due to self-templated additions at the 3’ end. Utilizing a PCR-like system to amplify the DNA template in large quantities eliminates the requirement for plasmid enrichment in bacteria, the prime source of endotoxin contamination. These are just a few examples of Cisterna’s powerful technologies being used to achieve our goal of 10x higher quality mRNA for therapeutic application.
San Diego, CA, USA
Cisterna Biologics: questions
Which YC batch was Cisterna Biologics in?
Cisterna Biologics was in Y Combinator's Summer 2022 batch (S22).
Is Cisterna Biologics still active?
Y Combinator lists Cisterna Biologics as active.
Where is Cisterna Biologics based?
Cisterna Biologics lists San Diego, CA, USA as its location on YC's directory.
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